Eric Dane, best known for his role as the charismatic Dr. Mark Sloan—aka McSteamy—on Grey’s Anatomy, has revealed that he has been diagnosed with amyotrophic lateral sclerosis (ALS), a rare neurodegenerative disease. “I have been diagnosed with ALS,” Dane told PEOPLE in an exclusive interview. “I am grateful to have my loving family by my side as we navigate this next chapter.”
ALS, commonly referred to as Lou Gehrig’s disease, is a progressive illness that targets motor neurons—nerve cells responsible for controlling voluntary muscle movements such as walking, speaking, swallowing, and breathing. Over time, the loss of these neurons leads to severe muscle weakness and paralysis.
The disease is relentless and currently has no cure. According to the Muscular Dystrophy Association, life expectancy after diagnosis is typically three to five years, although some individuals have lived significantly longer. Symptoms can begin subtly with muscle twitching or slurred speech, then gradually impact daily activities like climbing stairs or lifting objects.
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Who is Eric Dane married to, and how is his family supporting him?
Eric Dane, 52, was previously married to actress and model Rebecca Gayheart. The couple tied the knot in 2004 and share two daughters: Billie Beatrice, 15, and Georgia Geraldine, 13. Though they divorced in 2018 due to irreconcilable differences, Dane emphasized the importance of his family’s presence during this time. “I kindly ask that you give my family and I privacy during this time,” he said.
Their family life has previously been under the spotlight, particularly during a 2009 incident involving a leaked private video. Despite past controversies, Dane’s current public statements reflect a unified family front focused on navigating his diagnosis.
What happens when you have ALS?
ALS begins subtly. Patients might notice weakness in their hands or legs, or trouble speaking. As the disease progresses, the following symptoms tend to appear:
- Difficulty walking or climbing stairs
- Muscle cramps and twitching (fasciculations)
- Slurred or nasal speech
- Trouble swallowing and increased choking risk
- Progressive paralysis affecting mobility and breathing
- Emotional changes, including depression and inappropriate laughing or crying
Notably, ALS does not usually impair senses like vision or hearing, and many patients remain cognitively aware throughout the progression of the disease.
Did Eric Dane have cancer?
Despite the difficult news, Dane remains focused on his career. “I feel fortunate that I am able to continue working and am looking forward to returning to set of Euphoria next week,” he told PEOPLE. On Euphoria, he portrays Cal Jacobs, the complicated father of Jacob Elordi’s character, Nate. Season 3 production is set to resume on April 14.
This isn’t the actor’s first health scare. In 2008, Dane was diagnosed with skin cancer, which he successfully treated. He’s also openly spoken about battling depression and a prescription drug addiction, seeking professional help in 2011 and again in 2017.
What celebrities have ALS?
While rare—affecting about 7 in every 100,000 people—ALS has claimed and challenged the lives of several public figures. Notable celebrities with ALS include:
- Stephen Hawking – Renowned physicist who lived with ALS for over 50 years
- Kenneth Mitchell – Actor known for Star Trek: Discovery
- Roberta Flack – Iconic singer diagnosed in recent years
- Eric Stevens – Former NFL player
- Aaron Lazar – Broadway actor
- Joe Bonsall – Member of The Oak Ridge Boys
- John Driskell Hopkins – Musician from Zac Brown Band
Their experiences, like Dane’s, have brought much-needed attention to the disease and the urgent need for continued research.
What is Eric Dane’s net worth?
As of 2025, Eric Dane’s net worth is estimated at $7 million. He built his career steadily, first making appearances in shows like Saved by the Bell, Charmed, and Gideon’s Crossing. His breakout role came in 2006 on Grey’s Anatomy, where he remained a mainstay until season 9, with a fan-favorite return in season 17.
Post-Grey’s, Dane led The Last Ship (2014–2018) and became a key player in Euphoria. On the big screen, his resume includes X-Men: The Last Stand, Burlesque, Marley & Me, and Redeeming Love. His financial success stems from both television and film, along with endorsements and appearances.
How do you get ALS disease?
The exact cause of ALS remains largely unknown. Roughly 10% of cases are hereditary, linked to specific gene mutations. The remaining 90% are classified as sporadic, with no known family history. Potential risk factors include:
- Age – Most commonly diagnosed between 40 and 70
- Gender – Slightly more common in men
- Military service – Veterans are twice as likely to develop ALS
- Environmental exposures – Toxins and trauma may play a role
Scientists continue to study these links, but much remains uncertain.
How quickly does ALS progress?
The progression of ALS varies significantly from person to person. For some, the disease advances rapidly, while others may experience a slower decline. Generally, individuals lose the ability to walk, speak, and breathe independently within a few years.
Treatments like Riluzole (Rilutek) and Edaravone (Radicava) can slightly extend survival and improve quality of life. Physical therapy, speech assistance devices, nutritional support, and respiratory aids like BiPAP machines are commonly used to manage symptoms.
